The aim of the research, the results of which have been presented in this monograph, is related to both theoretical and methodological as well as cognitive and application levels. The theoretical and methodological objective is to provide a theoretical framework for a place-based approach in development policy which embraces the pattern of socio- economic development factors in the context of new challenges of regional policy. In addition, what has been presented is an algorithm of the research procedure that makes it possible to verify theoretical assumptions, which is based on a quantitative approach (the use of mathematical and statistical methods and spatial econometrics) and a qua-litative one (the use of qualitative research). The cognitive and application aim of the studies is a diagnosis of the state of the implementation of place-based policy in a less developed region, which is Wielkopolska, along with the identification of socioeconomic development factors in the context of new challenges of regional policy and producing recommendations concerning their use in practical intervention measu-res. The period of the conducted analyses covers various, depending on data accessi-bility, series of observations within 2004‑2018, allowing for the signalled historical determinants. In view of the existing restrictions on access to data in the examined spatial patterns and the period adopted, the results of the direct research are an import-ant complement to the geographical information database used in this study. The field studies were carried out in 2019 in the area of nine purposely selected communes of Wielkopolskie Voivodeship representing various development types.