Water sounds have always been, and are still nowadays, abso-lutely among the most appreciated natural sounds. Besides its mul-tiple types of emission in terms of loudness, temporal variation and spectral sound distribution, water sounds are rarely interpreted as a negative element. Furthermore, water sounds evoke positive sensations and ex-pectations, and the informational masking of water sounds is effec-tive in mitigating the adverse effects of noise. From a psycho- physiological perspective, listening to water sounds can improve the perceived Restorativeness of a place, induce neural relaxation, or activate the parasympathetic nervous system responsible for stress relief. This review analyses the role of water sound in multi-sensory environments through the investigation performed in several disci-plines. In the first part, we briefly describe the typologies of sounds generated by water, then the effects that water sounds can have on humans, and in the end, are presented the preliminary results of a study on the emotions elicited by water noise conducted at Isola del Liri, a unique historical village in central Italy where inhabitants cohabit daily with a waterfall noise.